Term Name: | germinal center B cell differentiation |
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Synonyms: | germinal center B cell development, germinal center B lymphocyte differentiation, germinal center B-cell differentiation, germinal center B-lymphocyte differentiation |
Definition: | The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA). |
Ontology: | GO: Biological Process [GO:0002314] QuickGO AmiGO |