Term Name: | T-helper 2 cell lineage commitment |
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Synonyms: | T-helper 2 cell fate commitment, Th2 fate commitment |
Definition: | The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy. |
Ontology: | GO: Biological Process [GO:0002297] QuickGO AmiGO |