Term Name: | cap-dependent translational initiation |
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Synonyms: | |
Definition: | The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation. |
Ontology: | GO: Biological Process [GO:0002191] QuickGO AmiGO |