Term Name: | B-1 B cell differentiation |
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Synonyms: | B-1 B cell development, B-1 B lymphocyte differentiation, B-1 B-cell differentiation, B-1 B-lymphocyte differentiation |
Definition: | The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. |
Ontology: | GO: Biological Process [GO:0001923] QuickGO AmiGO |