Term Name: | Werner syndrome |
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Synonyms: | adult premature ageing syndrome, adult progeria, Werner's syndrome, WS |
Definition: | A progeroid syndrome characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some types of cancers and that has_material_basis_in mutations in the WRN gene, on chromosome 8. |
Ontology: | Human Disease [DOID:5688] ( DOID:5688 ) |