Term Name: Ehlers-Danlos syndrome
Synonyms: Cutis hyperelastica, elastic skin
Definition: A collagen disease that is characterized by extremely flexible joints, elastic skin, and excessive bruising caused by a heritable defect in collagen synthesis, which leads to marked healing difficulties. EDS has five cardinal signs, which may be present to some degree in all of the subtypes. These five cardinal signs are skin fragility, blood vessel fragility, skin hyperelasticity, joint hypermobility, and characteristic subcutaneous nodules.
Ontology: Human Disease [DOID:13359]   ( DOID:13359 )

Relationships
is a type of: collagen disease
has subtype: autosomal recessive type IV Ehlers-Danlos syndrome brittle cornea syndrome 1 brittle cornea syndrome 2 Ehlers-Danlos syndrome arthrochalasia type 1 Ehlers-Danlos syndrome arthrochalasia type 2 Ehlers-Danlos syndrome cardiac valvular type Ehlers-Danlos syndrome classic type 1 Ehlers-Danlos syndrome classic type 2 Ehlers-Danlos syndrome classic-like 1 Ehlers-Danlos syndrome classic-like 2 Ehlers-Danlos syndrome dermatosparaxis type Ehlers-Danlos syndrome hypermobility type Ehlers-Danlos syndrome kyphoscoliotic type 1 Ehlers-Danlos syndrome kyphoscoliotic type 2 Ehlers-Danlos syndrome musculocontractural type 1 Ehlers-Danlos syndrome musculocontractural type 2 Ehlers-Danlos syndrome periodontal type 1 Ehlers-Danlos syndrome periodontal type 2 Ehlers-Danlos syndrome spondylodysplastic type 1 Ehlers-Danlos syndrome spondylodysplastic type 2 Ehlers-Danlos syndrome spondylodysplastic type 3 vascular type Ehlers-Danlos syndrome