Term Name: | graft-versus-host disease |
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Synonyms: | graft versus host disease, GvHD |
Definition: | An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32. |
Ontology: | Human Disease [DOID:0081267] ( DOID:0081267 ) |