Term Name:	pachygyria, microcephaly, developmental delay, and dysmorphic facies, with or without seizures
Synonyms:	PAMDDFS
Definition:	A lissencephaly that is characterized by progressive microcephaly associated with abnormal facial features, hypotonia, and variable global developmental delay with impaired intellectual development and that has_material_basis_in homozygous or compound heterozygous mutation in the TUBGCP2 gene on chromosome 10q26.
Ontology:	Human Disease [DOID:0081266]   ( DOID:0081266 )