Term Name: | multiple endocrine neoplasia type 4 |
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Synonyms: | Multiple Endocrine Neoplasia, Type IV |
Definition: | A multiple endocrine neoplasia that is characterized by hyperparathyroidism and multiple endocrine tumors and that has_material_basis_in mutations in the CDKN1B gene on chromosome 12p13 resulting in a reduction in the amount of functional p27 tumor suppressor protein which allows cells to grow and divide unchecked. |
Ontology: | Human Disease [DOID:0080137] ( DOID:0080137 ) |