Term Name: | NUT midline carcinoma |
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Synonyms: | nuclear protein in testis midline carcinoma |
Definition: | A carcinoma that is characterized by a BRD4-NUT translocation involving the rearrangement of the bromodomain-containing protein 4 (BRD4) and the gene encoding nuclear protein of the testis (NUT) at 15q14, BRD4-NUT t(15;19)(q14;q13.1) and arises from midline epithelial structures, most commonly the head, neck, and mediastinum. |
Ontology: | Human Disease [DOID:0060463] ( DOID:0060463 ) |