Term Name: | Lambert-Eaton myasthenic syndrome |
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Synonyms: | Eaton-Lambert syndrome, Lambert-Eaton syndrome, LEMS |
Definition: | A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal. |
Ontology: | Human Disease [DOID:0050214] ( DOID:0050214 ) |