Term Name: | T follicular helper cell |
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Synonyms: | follicular B helper T cell, follicular helper T cell, follicular helper T-cell, follicular T cell, follicular T-cell, follicular T-helper cell, T(FH), Tfh |
Definition: | A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that expresses is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production. |
Ontology: | Cell Ontology [CL:0002038] |