Term Name:	tramadol
Synonyms:	(+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol, CG-315E, E-265, rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol, tramadol, tramadolum, U-26225A
Definition:	A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Gruenenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia.
Ontology:	ChEBI [CHEBI:9648] ( EBI )

Relationships

is a type of:	racemate
has_part:	(R,R)-tramadol (S,S)-tramadol
has_role:	adrenergic uptake inhibitor antitussive capsaicin receptor antagonist delta-opioid receptor agonist environmental contaminant kappa-opioid receptor agonist mu-opioid receptor agonist muscarinic antagonist nicotinic antagonist NMDA receptor antagonist opioid analgesic serotonergic antagonist serotonin uptake inhibitor xenobiotic
inverse is_conjugate_acid_of:	tramadol(1+)
is_conjugate_base_of:	tramadol(1+)