Term Name: | PS-1145 |
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Synonyms: | IKK inhibitor X, N-(6-chloro-9H-beta-carbolin-8-yl)pyridine-3-carboxamide, N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide, N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)nicotinamide, N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)pyridine-3-carboxamide, PS 1145, PS1145 |
Definition: | A member of the class of beta-carbolines that is 9H-beta-carboline substituted by chloro and (pyridin-3-ylcarbonyl)amino groups at positions 6 and 8, respectively. It is a IkappaB kinase beta (IKKbeta) inhibitor (IC50 = 88 nM). |
Ontology: | ChEBI [CHEBI:94801] ( EBI ) |