Term Name: | pimasertib |
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Synonyms: | AS 703026, AS-703026, AS703026, MSC 1936369B, MSC-1236369B, MSC1936369B, N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)-4-pyridinecarboxamide, N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide, pimasertib, pimasertibum, SAR 245509, SAR-245509, SAR245509 |
Definition: | A secondary carboxamide resulting from the formal condensation of the carboxy group of 3-(2-fluoro-4-iodoanilino)pyridine-4-carboxylic acid with the amino group of (2S)-3-aminopropane-1,2-diol. It is a potent inhibitor of the mitogen-activated protein kinases MEK1 and MEK2 with potential antineoplastic activity. |
Ontology: | ChEBI [CHEBI:94793] ( EBI ) |