Term Name: | syrbactin |
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Synonyms: | syrbactins |
Definition: | A class of azamacrocyclic natural products with a 2,7-dioxo-1,6-diazacyclododecane skeleton that includes the syringolin, glidobactin and cepafungin natural product families. In addition to their related molecular frameworks, members of the class share similar biosynthesis pathways and identical modes-of-action, being irreversible proteasome inhibitor that inhibit all three activities of eukaryotic proteasomes. |
Ontology: | ChEBI [CHEBI:82671] ( EBI ) |