Term Name: | rac-crizotinib |
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Synonyms: | (+-)-crizotinib, (RS)-crizotinib, rac-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine, racemic crizotinib |
Definition: | A racemate comprising equimolar amounts of (R)- and (S)-crizotinib. The active (R)-enantiomer acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer. |
Ontology: | ChEBI [CHEBI:77563] ( EBI ) |