Term Name:	5-fluoroorotic acid
Synonyms:	1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro-4-pyrimidinecarboxylic acid, 5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid, 5-fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, 5-fluoro-6-carboxyuracil, 5-fluorouracil-4-carboxylic acid, ENT-26398, FO, FOA, NSC 31712, NSC-31712, Ro 2-9945
Definition:	A pyrimidinemonocarboxylic that is orotic acid which is substituted by fluorine at position 5. It is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate dicarboxylase. A yeast with and active URA3 gene converts 5-fluoroorotic acid to fluorodeoxyuridine, which is toxic to cells.
Ontology:	ChEBI [CHEBI:74498]  ( EBI )