Term Name: | masoprocol |
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Synonyms: | 4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol, Actinex, CHX 100, CHX-100, erythro-nordihydroguaiaretic acid, masoprocol, masoprocolum, meso-1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane, meso-2,3-bis(3,4-dihydroxyphenylmethyl)butane, meso-4,4'-(2,3-dimethyl-1,4-butanediyl)bis(pyrocatechol), meso-4,4'-(2,3-dimethyltetramethylene)dipyrocatechol, meso-4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol, meso-beta,gamma-dimethyl-alpha,delta-bis(3,4-dihydroxyphenyl)butan, meso-NDGA, meso-nordihydroguaiaretic acid |
Definition: | The meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase. |
Ontology: | ChEBI [CHEBI:73468] ( EBI ) |