Term Name: | midodrine |
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Synonyms: | (+-)-2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide, 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol, 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide, DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid, midodrina, midodrine, midodrinum, rac-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]glycinamide |
Definition: | An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine. |
Ontology: | ChEBI [CHEBI:6933] ( EBI ) |