Term Name: | lomustine |
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Synonyms: | 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea, 1-(2-chloroethyl)-3-cyclohexylnitrosourea, Belustine, CCNU, Cecenu, CeeNU, chloroethylcyclohexylnitrosourea, CINU, cyclohexyl chloroethyl nitrosourea, lomustina, lomustine, lomustinum, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea |
Definition: | An N-nitrosourea that is urea in which one of the nitrogens is substituted by a 2-chloroethyl group and by a nitroso group, while the other nitrogen is substituted by a cyclohexyl group. An alkylating antineoplastic agent, it is used in the treatment of brain tumours, lung cancer, malignant melanoma and other solid tumours. |
Ontology: | ChEBI [CHEBI:6520] ( EBI ) |