Term Name: | tenofovir (anhydrous) |
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Synonyms: | (R)-PMPA, ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid, anh. tenofovir, anhydrous tenofovir, tenofovir, tenofovir (anh.) |
Definition: | A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection. |
Ontology: | ChEBI [CHEBI:63625] ( EBI ) |