Term Name: | 2-hydroxy-4-methylvaleric acid |
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Synonyms: | 2-hydroxy-4-methylpentanoic acid, 2-hydroxyisocaproic acid, 2-hydroxyisohexanoic acid, alpha-Hydroxyisocaproic acid, Leucic acid, leucinic acid |
Definition: | A valeric acid derivative having a hydroxy substituent at the 2-position and a methyl substituent at the 4-position; an alpha-hydroxy analogue of leucine. A bacterial metabolite, it has also been isolated from amniotic fluid, was found in a patient with dihydrolipoyl dehydrogenase deficiency and is present in the urine of patients with short bowel syndrome. |
Ontology: | ChEBI [CHEBI:59783] ( EBI ) |