Term Name: | etacrynic acid |
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Synonyms: | (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid, [2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid, acide etacrynique, acido etacrinico, acidum etacrynicum, Crinuryl, Edecril, Edecrina, Endecril, Etacrinic acid, etacrynic acid, Ethacrynate, ethacrynic acid, Hidromedin, Hydromedin, Methylenebutyrylphenoxyacetic acid, Mingit, Otacril, Reomax, Taladren, Uregit |
Definition: | An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor. |
Ontology: | ChEBI [CHEBI:4876] ( EBI ) |