Term Name: | obeticholic acid |
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Synonyms: | (3alpha,5beta,6alpha,7alpha)-6-ethyl-3,7-dihydroxycholan-24-oic acid, 6-ECDCA, 6-Ethyl-CDCA, 6-Ethylchenodeoxycholic acid, 6alpha-ethyl-3alpha,7alpha-dihydroxy-5beta-cholan-24-oic acid, 6alpha-Ethyl-chenodeoxycholic acid, 6alpha-ethylchenodeoxycholic acid, INT 747, INT-747, INT747, obeticholic acid, Ocaliva |
Definition: | A dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis. |
Ontology: | ChEBI [CHEBI:43602] ( EBI ) |