Term Name: | crotamiton |
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Synonyms: | crotalgin, crotamiton, crotamitone, crotamitonum, crotonyl-N-ethyl-o-toluidine, N-ethyl-N-(2-methylphenyl)but-2-enamide, N-ethyl-o-crotonotoluidide |
Definition: | An enamide resulting from the formal condensation of crotonic acid with N-ethyl-2-methylaniline. A colourless or pale yellow oily liquid, it is used in the treatment of pruritus (itching) by producing a counter-irritation: as it evaporates from the skin, it produces a cooling effect that diverts attention away from the itching. It has also been used as an acaricide in the treatment of scabies, though more effective drugs are usually preferred. |
Ontology: | ChEBI [CHEBI:31439] ( EBI ) |