Term Name: | capmatinib |
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Synonyms: | 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, INC 280, INC-280, INC280, INCB 28060, INCB-28060, INCB-28060 free base, INCB28060 |
Definition: | A member of the class of imidazotriazines that is imidazo[1,2-b][1,2,4]triazine substituted by 3-fluoro-4-(methylcarbamoyl)phenyl and quinolin-6-ylmethyl groups at positions 2 and 7, respectively. It is a c-Met receptor tyrosine kinase inhibitor used for the treatment of non-small cell lung cancer with MET exon 14 skipping mutation. |
Ontology: | ChEBI [CHEBI:231693] ( EBI ) |