Term Name: | SH-1280 |
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Synonyms: | (2S)-2-(3,4-dimethoxyphenyl)-1-(5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)propan-1-one, (2S)-2-(3,4-dimethoxyphenyl)-1-(5-methoxy-2,2-dimethyl-2H-chromen-6-yl)propan-1-one, SH 1280, SH1280 |
Definition: | A chromene that is 2,2-dimethyl-2H-chromene substituted by methoxy and (2S)-2-(3,4-dimethoxyphenyl)propanoyl groups at positions 5 and 6, respectively. It is a Hsp90 inhibitor that prevents hypoxia-mediated retinal neovascularization and could potentially be used as a treatment for diabetic retinopathy. |
Ontology: | ChEBI [CHEBI:231662] ( EBI ) |