Term Name: | trofinetide |
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Synonyms: | (2S)-2-({[(2S)-1-(aminoacetyl)-2-methylpyrrolidin-2-yl]carbonyl}amino)pentanedioic acid, (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidine-2-carbonyl]amino}pentanedioic acid, Daybue, glycyl-2-methyl-L-prolyl-L-glutamic acid, NNZ 2566, NNZ-2566, NNZ2566, trofinetida, trofinetide, trofinetidum |
Definition: | A tripeptide comprising of glycine, 2-methyl-L-proline, and L-glutamic acid joined in sequence by peptide linkages. It is the first and only treatment approved by the FDA specifically indicated for Rett syndrome in adults and pediatric patients two years of age and older. |
Ontology: | ChEBI [CHEBI:229599] ( EBI ) |