Term Name: | daprodustat |
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Synonyms: | daprodustat, daprodustatum, GSK 1278863, GSK-1278863, GSK1278863, Jesduvroq, N-[(1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidin-5-yl)carbonyl]glycine, {[(1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidin-5-yl)carbonyl]amino}acetic acid |
Definition: | A member of the class of barbiturates that is barbituric acid substituted by cyclohexyl groups at positions 1 and 3, and by a (carboxymethyl)aminocarbonyl group at position 5. It is an inhibitor of hypoxia-inducible factor prolyl hydroxylase developed by GlaxoSmithKline for the treatment of anaemia in patients with chronic kidney disease. |
Ontology: | ChEBI [CHEBI:229223] ( EBI ) |