Term Name:	BAY11-7085
Synonyms:	(2E)-3-(4-tert-butylbenzene-1-sulfonyl)prop-2-enenitrile, (2E)-3-[(4-tert-butylphenyl)sulfonyl]prop-2-enenitrile, (2E)-3-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-2-propenenitrile, (E)-3-(4-t-butylphenylsulfonyl)-2-propenenitrile, (E)-3-(4-tert-butylphenylsulfonyl)-2-propenenitrile, Bay 11-7083, Bay 11-7085, Bay-11-7085, BAY-117085
Definition:	A sulfone that is benzene substituted by [(E)-2-cyanoethenyl]sulfonyl and tert-butyl groups at position 1 and 4, respectively. It is an irreversible inhibitor of IkappaB-alpha phosphorylation in cells (IC50 = 10 muM) and prevents the activation of NF-kappaB.
Ontology:	ChEBI [CHEBI:176500]  ( EBI )