Term Name: | ferrostatin-1 |
---|---|
Synonyms: | 3-amino-4-cyclohexylaminobenzoic acid ethyl ester, ethyl 3-amino-4-(cyclohexylamino)benzoate, Fer-1, ferrrostatin 1 |
Definition: | An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals. |
Ontology: | ChEBI [CHEBI:173086] ( EBI ) |