Term Name: | decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone |
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Synonyms: | dec-RVKR-cmk, decanoyl-Arg-Val-Lys-Arg-chloromethylketone, decanoyl-RVKR-CMK, N(2)-(1-oxodecyl)-L-arginyl-L-valyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-L-lysinamide, N(2)-decanoyl-L-arginyl-L-valyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-lysinamide |
Definition: | A tetrapeptide consisting of N-decanoyl-L-arginine, L-valine, L-lysine, and L-arginine joined in sequence by peptide linkages and in which the carboxy group at the C-terminus is substituted by a chloroacetyl group. It is a furin inhibitor that has antiviral activity against Chikungunya virus, Zika virus and Japanese encephalitis virus. |
Ontology: | ChEBI [CHEBI:156289] ( EBI ) |