Term Name: | Ro 5-3335 |
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Synonyms: | 7-chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 7-chloro-5-(2-pyrryl)-3H-1,4-benzodiazepin-2(H)-one, CBFbeta-Runx1 inhibitor II, Ro-5-3335, Ro5-3335 |
Definition: | A 1,4-benzodiazepinone that is nordazepam in which the phenyl substituent has been replaced by a 1H-pyrrol-2-yl group. It inhibits gene expression in HIV-1 at the transcriptional level through interference with Tat-mediated transactivation. |
Ontology: | ChEBI [CHEBI:131785] ( EBI ) |