Term Name: | N(alpha)-acetyl-N(tele)-(1,4-dihydroxynonan-3-yl)-L-histidine |
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Synonyms: | HNE-modified N-acetyl histidine, N(alpha)-acetyl-N(tele)-(1,4-dihydroxynonan-3-yl)-L-histidine, N-acetyl-1-(1,4-dihydroxynonan-3-yl)-L-histidine, N-acetyl-1-[2-hydroxy-1-(2-hydroxyethyl)heptyl]-L-histidine, N-acetyl-3-(1,4-dihydroxynonan-3-yl)-L-histidine, N-acetyl-3-[2-hydroxy-1-(2-hydroxyethyl)heptyl]-L-histidine |
Definition: | An L-histidine derivative in which the alpha-amino nitrogen of the amino acid has entered into amide formation with acetic acid and the tele- nitrogen carries a 1,4-dihydroxynonan-3-yl substituent. It has been synthesised by reaction of (E)-4-hydroxynon-2-enal (HNE) with N-acetyl-L-histidine, the tele nitrogen of histidine reacting with the double bond function of HNE via formation of a Michael adduct. |
Ontology: | ChEBI [CHEBI:131656] ( EBI ) |