| Name: | liver |
|---|---|
| Synonyms: | |
| Definition: | Solid compound organ with three lobes that has many functions including bile production, blood detoxification, the production of critical plasma proteins and clotting factors, complement proteins and the storage of many substances, such as lipids, amino acids, iron, and glycogen. Female fish produce vitellogenins in the liver. |
| Ontology: | Anatomy Ontology [ZFA:0000123] |
| Name: | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway |
|---|---|
| Synonyms: | NLR signaling pathway, NOD-like receptor signaling pathway, nucleotide-binding domain leucine-rich repeat containing receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signal transduction, nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway, nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway |
| Definition: | The series of molecular signals initiated by a ligand binding to a nucleotide-binding domain, leucine rich repeat containing receptor (NLR), and ending with the regulation of a downstream cellular process. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. |
| Ontology: | GO: Biological Process [GO:0035872] QuickGO AmiGO |