ZFIN ID: ZDB-EXP-220119-4 |
Experiment Conditions Description: cryoablation: cardiac ventricle, chemical treatment by injection: ilomastat
cryoablation: cardiac ventricle |
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Name: | cryoablation |
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Synonyms: | |
Definition: | Experimental condition which uses a cold instrument to ablate an anatomical structure or cell. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000249] |
Name: | cardiac ventricle |
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Synonyms: | ventricle |
Definition: | Cavitated compound organ that receives blood flow from the atrium and delivers blood to the body via the aorta. Valves are present to direct flow. There are only two chambers present in the fish heart. |
Ontology: | Anatomy Ontology [ZFA:0000009] |
chemical treatment by injection: ilomastat |
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Name: | chemical treatment by injection |
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Synonyms: | |
Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
Name: | ilomastat |
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Synonyms: | (2R)-N(4)-hydroxy-N(1)-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanediamide, CS 610, galardin, GM 6001, GM-6001, GM6001, ilomastat |
Definition: | An N-acyl-amino acid obtained by formal condensation of the carboxy group of (2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoic acid with the amino group of N-methyl-L-tryptophanamide. A cell permeable broad-spectrum matrix metalloproteinase (MMP) inhibitor |
Ontology: | ChEBI [CHEBI:137236] ( EBI ) |
Publication: | Xu et al., 2018 |
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