ZFIN ID: ZDB-EXP-220119-4
Experiment Conditions Description: cryoablation: cardiac ventricle, chemical treatment by injection: ilomastat
cryoablation: cardiac ventricle
Name: cryoablation
Synonyms:
Definition: Experimental condition which uses a cold instrument to ablate an anatomical structure or cell.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000249]
Name: cardiac ventricle
Synonyms: ventricle
Definition: Cavitated compound organ that receives blood flow from the atrium and delivers blood to the body via the aorta. Valves are present to direct flow. There are only two chambers present in the fish heart.
Ontology: Anatomy Ontology [ZFA:0000009]
chemical treatment by injection: ilomastat
Name: chemical treatment by injection
Synonyms:
Definition: Chemical treatment in which the chemical is injected into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000237]
Name: ilomastat
Synonyms: (2R)-N(4)-hydroxy-N(1)-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanediamide, CS 610, galardin, GM 6001, GM-6001, GM6001, ilomastat
Definition: An N-acyl-amino acid obtained by formal condensation of the carboxy group of (2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoic acid with the amino group of N-methyl-L-tryptophanamide. A cell permeable broad-spectrum matrix metalloproteinase (MMP) inhibitor
Ontology: ChEBI [CHEBI:137236]  ( EBI )
Publication: Xu et al., 2018