ZFIN

ZFIN ID: ZDB-EXP-200403-2

Experiment Conditions Description: transection: Mauthner neuron, chemical treatment by environment: EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor

transection: Mauthner neuron

Name:	transection
Synonyms:
Definition:	Cutting transversly of an organ or tissue. Type of cutting often used to divide the spinal cord to investigate neural regeneration in zebrafish.
Ontology:	Zebrafish Environment Condition Ontology [ZECO:0000181]

Name:	Mauthner neuron
Synonyms:
Definition:	Is a hindbrain interneuron. Giant reticulospinal neurons possessing thick crossed axons and positioned dorsally in the hindbrain tegmentum at the level of entrance of the eighth cranial nerve. The Mauthner neuron is paired. The M-cell has two large invariant dendrites: The lateral dendrite terminates in the sensory neuropil of the acoustico-lateral area, and the ventral dendrite terminates in the neuropil of the motor tegmentum. Fine dendrites are present, and mostly arise from three regions; from the terminus of each major dendrite and from the ventral surface of the perikaryon.
Ontology:	Anatomy Ontology [ZFA:0009149]

chemical treatment by environment: EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor

Name:	chemical treatment by environment
Synonyms:
Definition:	Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology:	Zebrafish Environment Condition Ontology [ZECO:0000238]

Name:	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
Synonyms:	ATP:protein phosphotransferase (MAPKK-activated) inhibitor, ATP:protein phosphotransferase (MAPKK-activated) inhibitors, c-Jun N-terminal kinase inhibitor, c-Jun N-terminal kinase inhibitors, Dp38 inhibitor, Dp38 inhibitors, EC 2.7.11.24 (mitogen-activated protein kinase) inhibitors, EC 2.7.11.24 inhibitor, EC 2.7.11.24 inhibitors, ERK inhibitor, ERK inhibitors, ERK1 inhibitor, ERK1 inhibitors, ERK2 inhibitor, ERK2 inhibitors, extracellular signal-regulated kinase inhibitor, extracellular signal-regulated kinase inhibitors, JNK inhibitor, JNK inhibitors, JNK3alpha1 inhibitor, JNK3alpha1 inhibitors, LeMPK3 inhibitor, LeMPK3 inhibitors, MAP kinase inhibitor, MAP kinase inhibitors, MAP-2 kinase inhibitor, MAP-2 kinase inhibitors, MAPK inhibitor, MAPK inhibitors, MBP kinase I inhibitor, MBP kinase I inhibitors, MBP kinase II inhibitor, MBP kinase II inhibitors, MEK inhibitor, MEK inhibitors, microtubule-associated protein 2 kinase inhibitor, microtubule-associated protein 2 kinase inhibitors, microtubule-associated protein kinase inhibitor, microtubule-associated protein kinase inhibitors, mitogen-activated protein kinase (EC 2.7.11.24) inhibitor, mitogen-activated protein kinase (EC 2.7.11.24) inhibitors, mitogen-activated protein kinase inhibitor, mitogen-activated protein kinase inhibitors, myelin basic protein kinase inhibitor, myelin basic protein kinase inhibitors, p38-2 inhibitor, p38-2 inhibitors, p38delta inhibitor, p38delta inhibitors, p42 mitogen-activated protein kinase inhibitor, p42 mitogen-activated protein kinase inhibitors, p42(mapk) inhibitor, p42(mapk) inhibitors, p44mpk inhibitor, p44mpk inhibitors, PMK-1 inhibitor, PMK-1 inhibitors, PMK-2 inhibitor, PMK-2 inhibitors, PMK-3 inhibitor, PMK-3 inhibitors, pp42 inhibitor, pp42 inhibitors, pp44(mapk) inhibitor, pp44(mapk) inhibitors, SAPK inhibitor, SAPK inhibitors, STK26 inhibitor, STK26 inhibitors, stress-activated protein kinase inhibitor, stress-activated protein kinase inhibitors
Definition:	An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).
Ontology:	ChEBI [CHEBI:79091] ( EBI )

Publication:	Bremer et al., 2019