| ZFIN ID: ZDB-EXP-190625-12 |
Experiment Conditions Description: transection: caudal fin, chemical treatment by environment: AH23848, chemical treatment by environment: prostaglandin E2
| transection: caudal fin |
|---|
| Name: | transection |
|---|---|
| Synonyms: | |
| Definition: | Cutting transversly of an organ or tissue. Type of cutting often used to divide the spinal cord to investigate neural regeneration in zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000181] |
| Name: | caudal fin |
|---|---|
| Synonyms: | tail, tail fin |
| Definition: | Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines. |
| Ontology: | Anatomy Ontology [ZFA:0001058] |
| chemical treatment by environment: AH23848 |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | AH23848 |
|---|---|
| Synonyms: | AH 23848, AH-23848, rac-(4Z)-7-[(1R,2R,5S)-5-[([1,1'-biphenyl]-4-yl)methoxy]-2-(morpholin-4-yl)-3-oxocyclopentyl]hept-4-enoic acid |
| Definition: | A racemate comprising equimolar amounts of (1R,2R,5S)- and (1S,2S,5R)-enantiomers of (4Z)-7-{5-[([1,1'-biphenyl]-4-yl)methoxy]-2-(morpholin-4-yl)-3-oxocyclopentyl}hept-4-enoic acid. The hemicalcium salt is a potent, specific thromboxane receptor-blocking drug that is orally active and has a long duration of action. |
| Ontology: | ChEBI [CHEBI:90388] ( EBI ) |
| chemical treatment by environment: prostaglandin E2 |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | prostaglandin E2 |
|---|---|
| Synonyms: | (15S)-prostaglandin E2, (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate, (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate, (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid, (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid, Cervidil, Cerviprime, Cerviprost, Dinoproston, dinoprostona, dinoprostone, dinoprostonum, Enzaprost E, Glandin-E2, Minprositin E2, Minprostin E2, PGE2, Prepidil, Propess, Prostaglandin E2, Prostarmon E, Prostenone, Prostin, Prostin E2, U 12062, U-12,062, U-12062 |
| Definition: | Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins. |
| Ontology: | ChEBI [CHEBI:15551] ( EBI ) |
| Publication: | Loynes et al., 2018 |
|---|