| ZFIN ID: ZDB-EXP-190530-4 |
Experiment Conditions Description: chemical treatment by injection: BCI-215, resection: cardiac ventricle
| chemical treatment by injection: BCI-215 |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | BCI-215 |
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| Synonyms: | (2E)-2-benzylidene-5-bromo-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one |
| Definition: | An aromatic ketone that is 2,3-dihydro-1H-inden-1-one which is substituted at positions 2, 3, and 5 by (E)-benzylidene, cyclohexylamino, and bromine, respectively. A hyperactivator of fibroblast growth factor signaling in transgenic zebrafish that is devoid of developmental toxicity and restores defective MAPK activity caused by overexpression of DUSP1 and DUSP6 in mammalian cells. |
| Ontology: | ChEBI [CHEBI:143128] ( EBI ) |
| resection: cardiac ventricle |
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| Name: | resection |
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| Synonyms: | |
| Definition: | Surgical manipulation in which a particular organ, appendage, or part of an organism is removed. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000171] |
| Name: | cardiac ventricle |
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| Synonyms: | ventricle |
| Definition: | Cavitated compound organ that receives blood flow from the atrium and delivers blood to the body via the aorta. Valves are present to direct flow. There are only two chambers present in the fish heart. |
| Ontology: | Anatomy Ontology [ZFA:0000009] |
| Publication: | Missinato et al., 2018 |
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