| ZFIN ID: ZDB-EXP-190401-1 |
Experiment Conditions Description: chemical treatment by injection: PDGF receptor tyrosine kinase inhibitor III, resection: cardiac ventricle
| chemical treatment by injection: PDGF receptor tyrosine kinase inhibitor III |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | PDGF receptor tyrosine kinase inhibitor III |
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| Synonyms: | 4-(6,7-dimethoxyquinazolin-4-yl)-N-(4-phenoxyphenyl)piperazine-1-carboxamide, N-(4-phenoxyphenyl)-4-(6,7-dimethoxyquinazoline-4-yl)piperazine-1-carboxamide, PDGFR tyrosine kinase inhibitor III |
| Definition: | An N-arylpiperazine that is piperazine in which the hydrogen attached to the nitrogen at position 1 is replaced by a (4-phenoxyphenyl)aminocarbonyl group, while the hydrogen attached to the nitrogen at position 4 is replaced by a 6,7-dimethoxyquinazolin-4-yl group. It is an inhibitor of tyrosine kinases FLT3, PDGFR and KIT. |
| Ontology: | ChEBI [CHEBI:143127] ( EBI ) |
| resection: cardiac ventricle |
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| Name: | resection |
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| Synonyms: | |
| Definition: | Surgical manipulation in which a particular organ, appendage, or part of an organism is removed. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000171] |
| Name: | cardiac ventricle |
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| Synonyms: | ventricle |
| Definition: | Cavitated compound organ that receives blood flow from the atrium and delivers blood to the body via the aorta. Valves are present to direct flow. There are only two chambers present in the fish heart. |
| Ontology: | Anatomy Ontology [ZFA:0000009] |
| Publication: | Missinato et al., 2018 |
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