| ZFIN ID: ZDB-EXP-170915-7 |
Experiment Conditions Description: chemical treatment by environment: Cyclopamine, chemical treatment by environment: calciol
| chemical treatment by environment: Cyclopamine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | Cyclopamine |
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| Synonyms: | Cyclopamine |
| Definition: | |
| Ontology: | ChEBI [CHEBI:4021] ( EBI ) |
| chemical treatment by environment: calciol |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | calciol |
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| Synonyms: | (+)-vitamin D3, (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL, (3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol, (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol, activated 7-dehydrocholesterol, calciol, CC, Cholecalciferol, colecalciferol, Delta-D, oleovitamin D3, Vitamin D3 |
| Definition: | A hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone. |
| Ontology: | ChEBI [CHEBI:28940] ( EBI ) |
| Publication: | Cortes et al., 2015 |
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