| ZFIN ID: ZDB-EXP-160527-9 |
Experiment Conditions Description: chemical treatment: entinostat
| chemical treatment: entinostat |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | entinostat |
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| Synonyms: | BAY 86-5274, BAY86-5274, entinostat, entinostatum, MS 27-275, MS 275, MS-27-275, MS-275, N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide, N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester, pyridin-3-ylmethyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate, SNDX 275, SNDX-275 |
| Definition: | A member of the class of benzamides resulting from the formal condensation of the carboxy group of the pyridin-3-ylmethyl carbamate derivative of p-(aminomethyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an inhibitor of histone deacetylase isoform 1 (HDAC1) and isoform 3 (HDAC3). |
| Ontology: | ChEBI [CHEBI:132082] ( EBI ) |
| Publication: | Pinho et al., 2016 |
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