| ZFIN ID: ZDB-EXP-151120-4 |
Experiment Conditions Description: organ culture: testis, chemical treatment: BW 245C
| organ culture: testis |
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| Name: | organ culture |
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| Synonyms: | |
| Definition: | In vitro culture condition in which an organ is dissected/isolated/collected from the fish and placed in culture. The analysis of the experiment is done on this organ in culture. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000144] |
| Name: | testis |
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| Synonyms: | testes |
| Definition: | Male reproductive organ. Adult zebrafish testes are paired organs forming elongated structures, internally organized into tubules. These tubules are formed by seminiferous epithelium containing cysts of spermatogonia and spermatocytes surrounded by somatic support cells, called Sertoli cells. Cysts are arranged around a lumen containing spermatozoa that is connected to the efferent ducts. The interstitial regions between the tubules contain the steroid-producing Leydig cells, connective tissue, and blood vessels. |
| Ontology: | Anatomy Ontology [ZFA:0000598] |
| chemical treatment: BW 245C |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | BW 245C |
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| Synonyms: | (+-)-BW 245C, rac-7-{(4S)-3-[(3R)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxoimidazolidin-4-yl}heptanoic acid, rac-BW 245C |
| Definition: | A racemate comprising equimolar amounts of (3R,4S)- and (3S,4R)-BW 245C. A hydantoin-based prostglandin analogue. |
| Ontology: | ChEBI [CHEBI:131496] ( EBI ) |
| Publication: | Pradhan et al., 2014 |
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