| ZFIN ID: ZDB-EXP-151106-7 |
Experiment Conditions Description: chemical treatment: doxycycline monohydrate, chemical treatment: NF-kappaB inhibitor
| chemical treatment: doxycycline monohydrate |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | doxycycline monohydrate |
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| Synonyms: | (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide--water (1/1), doxycycline, doxycycline hydrate |
| Definition: | The monohydrate form of doxycycline. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. |
| Ontology: | ChEBI [CHEBI:60648] ( EBI ) |
| chemical treatment: NF-kappaB inhibitor |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | NF-kappaB inhibitor |
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| Synonyms: | NF-kappaB inhibitors, nuclear factor kappa-light-chain-enhancer of activated B cells inhibitor, nuclear factor kappa-light-chain-enhancer of activated B cells inhibitors |
| Definition: | An inhibitor of NF-kappaB (nuclear factor kappa-light-chain-enhancer of activated B cells), a protein complex involved in the transcription of DNA. |
| Ontology: | ChEBI [CHEBI:73240] ( EBI ) |
| Publication: | Yan et al., 2015 |
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