| Name: |
CK-666 |
| Synonyms: |
2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide,
CK 666,
CK-0944666,
CK666
|
| Definition: |
A member of the class of indoles that is 2-methyltryptamine in which a hydrogen attached to the primary amino group has been replaced by a 2-fluorobenzoyl group. It is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex which works by binding to Arp2/3 complex, stabilising the inactive state of the complex and preventing its movement into the active conformation. |
| Ontology: |
ChEBI [CHEBI:78843]
(
EBI
)
|