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Fig. 4
gars-KD zebrafish larvae have low motility.
(A) Simplified diagram showing how to use the DanioVision system to analyze zebrafish behaviors that occur when they respond to light stimulation. (B) Heatmap images comparing swimming patterns between control and gars MOs-injected larvae recorded for 30 min. (C) Quantification of velocity measured in zebrafish larvae injected with control MOs (n = 57), gars MOs (n = 47), and gars MOs with human WT GARS (n = 56) mRNAs. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post hoc test. *P < 0.05; ***P < 0.001. ns, non-significant.
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