Phenotype: | hepatocyte rough endoplasmic reticulum increased amount, abnormal |
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Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
Name: | hepatocyte |
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Synonyms: | hepatocytes |
Definition: | The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. |
Ontology: | Anatomy Ontology [ZFA:0009111] |
Name: | rough endoplasmic reticulum |
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Synonyms: | RER, rough ER |
Definition: | The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae. |
Ontology: | GO: Cellular Component [GO:0005791] QuickGO AmiGO |
Name: | increased amount |
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Synonyms: | accessory, increased, increased number, present in greater numbers in organism, supernumerary |
Definition: | An amount which is relatively high. |
Ontology: | Phenotypic Quality Ontology [PATO:0000470] |