| Phenotype: | DEL adherens junction disorganized, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | DEL |
|---|---|
| Synonyms: | deep cell layer, DEL cells |
| Definition: | A multilayer of deep cells of fairly uniform thickness that forms during early epiboly (at dome stage; upon conversion of the blastodisc to the blastoderm); during gastrulation the DEL (deep cell layer) gives rise to the epiblast and hypoblast. |
| Ontology: | Anatomy Ontology [ZFA:0000711] |
| Name: | adherens junction |
|---|---|
| Synonyms: | cell-cell adherens junction |
| Definition: | A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules. |
| Ontology: | GO: Cellular Component [GO:0005912] QuickGO AmiGO |
| Name: | disorganized |
|---|---|
| Synonyms: | |
| Definition: | A structural quality inhering in a bearer by virtue of the bearer's lacking organisation. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000937] |