Phenotype: | scavenger receptor activity disrupted, abnormal |
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Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
Name: | scavenger receptor activity |
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Synonyms: | macrophage receptor activity |
Definition: | Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs). |
Ontology: | GO: Molecular Function [GO:0005044] QuickGO AmiGO |
Name: | disrupted |
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Synonyms: | |
Definition: | A quality of a single process inhering in a bearer by virtue of the bearer's being interrupted of its normal course. |
Ontology: | Phenotypic Quality Ontology [PATO:0001507] |